Data Inputs

To have data to be used as input for Connected Multiomics, data can be:

Use data from DRAGEN pipeline

Connected Multiomics uses data from DRAGEN pipelines within the Illumina Connected ecosystem.

When kicking off DRAGEN pipelines in BaseSpace, ensure the same workgroup is used in BaseSpace as Connected Multiomics so that the DRAGEN outputs are visible to Connected Multiomics. To change the workgroup on BaseSpace, select the desired workgroup in the top right-hand corner.

If DRAGEN pipeline are kicked off in ICA or in BaseSpace using Personal, these results can be shared with the workgroup by adjusting the permissions set as indicated in the Add data from ICA project section.

Add data from ICA project

Connected Multiomics inputs are the results of secondary analysis pipelines that are stored on projects in Illumina Connected Analytics (ICA). Secondary analysis results may be generated from auto-launched pipelines, run manually or come from other sources such as legacy pipelines or commercial applications.

To access ICA in your software, select the Illumina Connected Analytics application tile from your Product Dashboard. For guidance on uploading and managing data in ICA, please refer to the instructions here. For data types and files format supported for analysis in the Connected Multiomics, please refer Supported Data Types.

To ensure users can proceed smoothly with their data exploration in Connected Multiomics, the workgroup that is in use in Connected Multiomics needs to be added to the ICA Project(s) at Team settings, with the following permissions set:

After data files are uploaded and workgroup is added, you may click on the Product Dashboard icon to navigate to Illumina Connected Multiomics to start working on your data.

Add data from local drive

In a Connected Multiomics study, click on Add Data and choose Upload local files

There are two options:

  • Upload files and add to study: the wizard will guide you create samples in a study after the files are uploaded

  • Upload files on: files will be stored in an ICA project. If you want to create samples from those files later, you need to choose "Select from ICA project" when you create samples

  • When choosing the first option, data type needs to be specified

  • From the data type drop-down list, specify technology, assay from the menu and the supported file types will be displayed

Select file format and click Continue

The files will be uploaded to ICA, specify an ICA project folder and drag & drop files from your local device or click on the Browse Files button to select files, click Upload to ICA

A progress bar will be displayed during uploading, once it is done, the status is displayed as Uploaded

Files will be uploaded to the folder of the ICA project name, subfolder "uploads" and ICM project name subfolder

Click on Ingest to Study to generate samples in the study.

Transfer data from public BaseSpace

If the data is in BaseSpace in public domain, see instructions on how to transfer data to an enterprise domain.

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