Adding a Variant Effect Predictor (VEP) Database

Click the + Add VEP database button under the VEP database section on the library file management pagearrow-up-right.

If you are using an species supported by Connected Multiomics (i.e., human, mouse), a VEP database from ENSEMBLarrow-up-right will be available for automatic download. Select the Download database radio button and click Create (Figure 1).

Figure 1. For certain model organisms, automatic downloads of VEP databases are available.

If you are working with a custom assembly, choose the Import database radio button and click Create (Figure 1). A VEP database can be added from your local computer by clicking the option of My Computer. ENSEMBL maintains an extensive list of VEP databases for various species. We recommend going to ENSEMBL's ftp download sitearrow-up-right and finding the VEP database download link for your species of interest.

One VEP database is allowed per genome assembly. Once a VEP is successfully imported, the + Add VEP database button will not be shown (Figure 2).

Figure 2. Successful addition of a VEP database library file.

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